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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: VDR All Species: 21.52
Human Site: S376 Identified Species: 52.59
UniProt: P11473 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P11473 NP_000367.1 427 48289 S376 C R H P P P G S H L L Y A K M
Chimpanzee Pan troglodytes A2T7D9 348 39540 G298 T L Q S Y I K G Q Q R R P R D
Rhesus Macaque Macaca mulatta Q8SQ01 434 49974 Q383 Y I E C N R P Q P A H R F L F
Dog Lupus familis XP_543714 448 49978 S397 C R H P P P G S H L L Y A K M
Cat Felis silvestris
Mouse Mus musculus P48281 422 47833 S371 C R H P P P G S H Q L Y A K M
Rat Rattus norvegicus P13053 423 47795 S372 C R H P P P G S H Q L Y A K M
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus O42392 451 51281 S400 C R H P P P G S R L L Y A K M
Frog Xenopus laevis O13124 422 48170 S371 C K H P P P G S R L L Y A K M
Zebra Danio Brachydanio rerio Q9PTN2 453 50848 G402 I R I Q H P G G R L L Y A K M
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus NP_001123279 490 55735 D431 Q M Q E T Y L D M L R S Y L K
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 35.1 39.8 88.3 N.A. 88.5 89.6 N.A. N.A. 76 73.3 67.9 N.A. N.A. N.A. N.A. 30.2
Protein Similarity: 100 51.9 56.2 91.7 N.A. 93.2 93.4 N.A. N.A. 84.4 85 78.8 N.A. N.A. N.A. N.A. 48.7
P-Site Identity: 100 0 0 100 N.A. 93.3 93.3 N.A. N.A. 93.3 86.6 60 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 6.6 0 100 N.A. 93.3 93.3 N.A. N.A. 93.3 93.3 60 N.A. N.A. N.A. N.A. 6.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 10 0 0 70 0 0 % A
% Cys: 60 0 0 10 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 10 0 0 0 0 0 0 10 % D
% Glu: 0 0 10 10 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 10 % F
% Gly: 0 0 0 0 0 0 70 20 0 0 0 0 0 0 0 % G
% His: 0 0 60 0 10 0 0 0 40 0 10 0 0 0 0 % H
% Ile: 10 10 10 0 0 10 0 0 0 0 0 0 0 0 0 % I
% Lys: 0 10 0 0 0 0 10 0 0 0 0 0 0 70 10 % K
% Leu: 0 10 0 0 0 0 10 0 0 60 70 0 0 20 0 % L
% Met: 0 10 0 0 0 0 0 0 10 0 0 0 0 0 70 % M
% Asn: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 60 60 70 10 0 10 0 0 0 10 0 0 % P
% Gln: 10 0 20 10 0 0 0 10 10 30 0 0 0 0 0 % Q
% Arg: 0 60 0 0 0 10 0 0 30 0 20 20 0 10 0 % R
% Ser: 0 0 0 10 0 0 0 60 0 0 0 10 0 0 0 % S
% Thr: 10 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 10 0 0 0 10 10 0 0 0 0 0 70 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _